The Future of Pet Probiotics Starts Here

Targeted. Tested. Trusted. Because your dog deserves a microbiome
designed by nature and validated by science.

As a functional medicine veterinarian focusing on root-cause healing, I've spent decades helping animals reclaim their health by working with their biology, not against it. That process begins in the gut, where trillions of microorganisms influence every aspect of your pet’s health: digestion, immunity, metabolism, cognition, and even behavior.

But not all probiotics are created equal. Most pet probiotics on the market are human strains—never adapted to the metabolic, immune, or thermal environment of dogs or cats. They’re not designed to survive the journey through a carnivore’s GI tract. And many lack evidence of efficacy in the species they’re sold for.

That’s why I developed PRIMITIVE PROBIOTICS™, a radically different, science-driven approach to rebuilding your dog’s microbiome using the very strains nature intended: from wild canids, healthy domestic dogs, and living soil.

Emerging research now confirms that species-specific probiotics, isolated from healthy members of the same species, offer more targeted benefits. These strains are naturally adapted to the host animal’s microbiome, pH, bile levels, temperature, and immune landscape.

Inspired by Nature. Backed by Science. Built for Dogs.

Primitive Probiotics™ blends three distinct microbial ecosystems that together create a resilient, well-adapted, and functional gut flora:


1. Ancestral Strains

These strains are isolated from wild wolves and represent the ancient microbial allies that dogs evolved with: robust, immune-priming, and genetically aligned with the canine body.

2. Species-Specific Strains

Sourced from healthy domestic dogs, these strains are uniquely adapted to the stressors and diets of modern life. They’re highly colonizable and provide targeted support for digestion, immunity, and stress tolerance.

3. Soil-Based Organisms (SBOs)

Spore-forming probiotics like Bacillus subtilis and Bacillus clausii are natural survivors. They resist heat, stomach acid, and antibiotics; modulating inflammation and restoring balance when your dog needs it most.

This triad is more than just a probiotic; it’s a complete microbiome restoration system. Together, they create a truly adaptive, robust, and functional microbiome for modern dogs.

Why Three Types of Microbes Matter

Type Source Function
Ancestral Strains Wild canids (wolves) Align with the evolutionary canine gut ecosystem
Species-Specific Strains Healthy domestic dogs Optimized for modern pet lifestyles and diets
Soil-Based Organisms (SBOs) Natural soil environments Resilient, enzyme-producing, immune-regulating

This triple-ecosystem approach restores microbial biodiversity, something no single-strain or lab-grown formula can achieve.

The Clinically Studied Strains That Power PRIMITIVE PROBIOTICS™

Every strain was selected for its specific functional benefit and survivability in the canine gastrointestinal tract.

Lactobacillus fermentum K9-2

Improves stool quality, supports gut barrier integrity, and reduces inflammation.

Lactobacillus casei K9-1

Balances gut flora, reduces Clostridium spp., and works synergistically with L. fermentum.

Lactobacillus reuteri PCR7

Produces reuterin (a natural antimicrobial), supports immune modulation and oral health.

Pediococcus acidilactici PCLL01

Survives gastric acid, reduces gas and diarrhea, supports microbial diversity.

Bifidobacterium spp.

Ferments fiber into SCFAs, enhances immunity, reduces gut inflammation in dogs and cats.

Optibiome® BS50 Bacillus subtilis

Improves stool consistency, nutrient digestion, and antioxidant status.

MuniSpore® Bacillus clausii CS108

Resistant to antibiotics and stomach acid; reduces diarrhea and supports gut and respiratory immunity.

Lactobacillus rhamnosus GG

One of the world’s most researched strains; reduces allergic reactivity and supports the gut-brain axis.

Saccharomyces boulardii

Probiotic yeast that halts diarrhea, protects the gut lining, and reduces inflammation.

Lactiplantibacillus plantarum LP815 (GABA Probiotic)

Produces GABA—a natural calming compound that regulates mood, sleep, and aggression

New: GABA Probiotic LP815™

sleeping puppy

For Calmer, More Emotionally Balanced Dogs

LP815 is a breakthrough probiotic strain that naturally produces GABA (gamma-aminobutyric acid); an inhibitory neurotransmitter that calms the nervous system by regulating how quickly neurons fire. Unlike traditional calming supplements, this probiotic acts within the gut, creating a lasting calming effect through the gut–brain axis.

LP815 Clinical Results in Dogs:

  • 46% of dogs had anxiety; 26% had aggression at baseline
  • After 4 weeks on LP815, dogs had:
    • Reduced fear- and noise-based aggression
    • More restful and consistent sleep
    • Improved mood and reduced reactivity
    • Better energy and emotional balance
    • Faster settling after owner departure

Zero adverse effects were reported in over 1,120 doses. Dogs of all breeds and diets tolerated it extremely well.

Can PRIMITIVE PROBIOTICS™ Help My Dog?

PRIMITIVE PROBIOTICS™ for Dog

PRIMITIVE PROBIOTICS™ is ideal for:

  • Dogs with diarrhea, soft stools, or excessive gas
  • Dogs recovering from antibiotics, illness, or stress
  • Dogs receiving heartworm parasiticides or flea/tick medications that can alter microbiota
  • Dogs with anxiety, aggression, or sleep issues
  • Seniors needing immune and cognitive support
  • Puppies building a resilient microbiome from the start

Canine-Derived Strains for Modern Dogs: Precision for the Present

dog check up

Today’s domestic dogs face modern challenges their wild counterparts never encountered:

  • Frequent antibiotic/medication exposure that disrupts the microbiome
  • Urban environments, increased environmental pollutants
  • Highly processed diets
  • Chronic low-grade inflammation
  • Reduced microbial diversity due to indoor lifestyles

Summary of Canine Strain Benefits:

dog interacting with the owner
  • Increases beneficial gut bacteria
  • Reduces harmful pathogens
  • Strengthens gut barrier and tight junctions
  • Supports digestion, immunity, and metabolism
  • Backed by multi-trial clinical research in dogs
  • FDA GRAS and Health Canada VHP compliant
  • Adapted to survive and thrive in your dog’s gut

Results You Can See

  • lying dog
    24–48 Hours:

    Noticeably firmer stool, less gas and bloating

  • dog eating food
    1–2 Weeks:

    Calmer mood and better appetite

  • dog running
    4+ Weeks:

    Stronger immunity, more energy, improved sleep, better resilience

Why Vets Trust PRIMITIVE PROBIOTICS™

primative probiotics for dog
  • Designed by a functional medicine veterinarian and microbiome scientists
  • Built for the canine gut, not repurposed from human formulas
  • Third-party tested for purity, viability, and shelf stability
  • Free from fillers, preservatives, or synthetic flavors
  • Safe for long-term use in all breeds and life stages
  • Safety-certified: evaluated under FDA GRAS and Health Canada List C veterinary health standards
  • Clinically backed: supported by multi-site trials using real-world canine models, not rodents or petri dishes
  • Manufactured in the USA in a GMP-certified facility, following strict quality and safety guidelines to ensure purity, potency, and consistency
  • 30-day “Love it or return it” policy

Gut Health Is the Missing Link

If your dog struggles with allergies, anxiety, chronic GI issues, or low energy, start by restoring the microbiome. A balanced gut fuels every system in the body, from immune strength to emotional regulation.

What’s NOT in PRIMITIVE PROBIOTICS

With common gut conditions like small intestine bacterial overgrowth (SIBO), prebiotics can worsen symptoms because they act as fuel for bacteria in the small intestine (good and bad alike), intensifying bloating, gas and discomfort. However, certain targeted probiotics may help by shifting the microbial balance, reducing populations of harmful species, and supporting gut barrier function without feeding the overgrowth. Strains such as Saccharomyces boulardii or specific soil-based spore-forming bacteria are less ikely to contribute to excessive fermentation and may aid in crowding out problematic microbes while calming inflammation, making them a more strategic choice than prebiotics during active SIBO. For this reason, we don’t include prebiotics in our formula.

PRIMITIVE PROBIOTICS™ isn’t just a supplement, it’s a strategy to support lifelong vitality from the inside out.

Give your dog the microbiome they were born to have.