Roe Mega DHA/EPA

Roe Mega DHA/EPA

Formulated by Dr. Karen Becker to address the specific needs of pets, delivering highly bioavailable omega-3s and antioxidant support for lifelong cellular, skin, joint, kidney, heart, and cognitive health.

Regular price $39.95 USD
Sale price $39.95 USD Regular price $43.95 USD
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Product Information

  • Roe Mega is formulated to respect your small pet’s biological design, delivering omega 3s in their most natural form through caviar oil, one of nature’s richest sources of phospholipid bound EPA and DHA, combined with clean, sustainably harvested small fish oils from sardines, anchovies, and mackerel.
  • Sustainably sourced and protected with natural astaxanthin to preserve freshness and potency, thoughtfully packaged in glass, not plastic, to help minimize microplastic exposure and deliver a cleaner, species-appropriate EPA and DHA your pet’s body can truly benefit from.
  • Cats are obligate carnivores, and their bodies rely on naturally occurring fats, especially omega 3 fatty acids, to maintain cellular integrity, control inflammation, and support skin, joint, immune balance, kidney, and cognitive health throughout life.
  • Astaxanthin, a naturally occurring carotenoid antioxidant, provides critical protection against oxidative stress, supports skin, brain, kidney, and cellular health, and works synergistically with omega‑3s to help maintain a balanced inflammatory response.
  • Roe Mega’s unique formulation was designed to deliver Specialized Pro-resolving Mediators (SPMs), which most fish oil products lack. These compounds don’t just reduce inflammation they actively resolve it at its source by turning off inflammatory signals, clearing damaged cells, and restoring normal tissue function, helping prevent inflammation from becoming chronic.
  • Veterinary‑formulated, clean, and species‑appropriate, highly bioavailable phospholipids, Roe Mega is precisely dosed, easy to administer, naturally palatable, and designed to support lifelong wellness by working with your cat’s or small dog’s body.

Direction of Use

Start by adding a few drops to food, and gradually increase to a full dose. Add the recommended amount to food twice daily for a maintenance dose. For a therapeutic dose, give double the maintenance amount the same dose applies to small dogs.

  • 2-4 lbs - 1/4 dropper 2x daily
  • 4-8 lbs - 1/2 dropper 2x daily
  • 8-12 lbs - 1 dropper 2x daily
  • 12-18 lbs - 1 1/4  droppers 2x daily
  • 18-22 lbs - 1 1/2 droppers 2x daily

Product Ingredients

Active Ingredients:

  • Omega-3 Fatty Acids
  • [Caviar Oil Extract1 (Herring), Fish Oil2 (Anchovy, Sardine, Mackerel)]
  • Astaxanthin
  • (Haematococcus pluvialis Microalgae Extract)

Inactive Ingredients:

  • Medium Chain Tricglyceride Oil, Tocopherols (as preservative)
  • Fresh until April 2029
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Advanced Omega-3 Support for Whole-Body Wellness

gray cat green eyes sitting-bed

Roe Mega is a veterinary-formulated omega-3 supplement designed to deliver a highly bioavailable blend of sustainably sourced marine-based nutrients to support optimal health at every stage of life. This unique formula combines nutrient-dense caviar oil with EPA and DHA from anchovies, sardines, and mackerel, creating a rich spectrum of essential fatty acids that work synergistically to nourish your pet from the inside out. Enhanced with astaxanthin, a powerful, stabilizing antioxidant, Roe Mega offers comprehensive support for cellular health, inflammation balance, and long-term vitality.

Unlike many conventional fish oil supplements, Roe Mega provides omega-3s in their most natural and biologically appropriate form. Caviar oil is naturally rich in phospholipid-bound EPA and DHA, which are more easily absorbed and utilized. These essential fats play a critical role in maintaining healthy skin and coat, supporting joint mobility, promoting kidney and cardiovascular health, and helping regulate immune function.

For cats and small dogs struggling with dry skin, excessive shedding, or inflammatory conditions, consistent omega-3 support can make a noticeable difference. It can also be a valuable addition for aging pets, helping to maintain mobility and mental sharpness while supporting a healthy inflammatory response. Because this formula works at the cellular level, it provides gentle, foundational support throughout the body.

Astaxanthin adds a powerful layer of protection for both your pet and the formula itself. This potent carotenoid antioxidant helps neutralize free radicals, reduce oxidative stress, and support skin, brain, kidney, and cellular health, while working synergistically with omega-3 fatty acids to promote a balanced inflammatory response.

Just as importantly, astaxanthin helps stabilize these delicate oils, protecting them from oxidation and preserving their freshness, potency, and biological integrity while using. And because this liquid is packaged in glass, not plastic, it avoids the microplastic contamination that inevitably occurs when oil-based products come into contact with plastic, ensuring a cleaner, safer delivery system from start to finish.

Not All Omega-3s Finish the Job: Why SPMs Are the Missing Link

Most omega-3 supplements stop at delivering EPA and DHA, which are important building blocks, but not the final step your pet’s body needs to truly resolve inflammation. Specialized pro-resolving mediators (SPMs) are the next-level compounds made from those fatty acids that actively switch off inflammation and guide the body back to balance. The catch is that SPMs are fragile, difficult to stabilize, and significantly more expensive to source and formulate, which is why they’re missing from the vast majority of fish oil products on the market. Instead, most products rely on your pet’s body to convert EPA and DHA into SPMs, a process that can be inefficient, especially in animals already dealing with chronic inflammation. By directly providing SPMs, you’re not just supporting inflammation; you’re helping complete the resolution process at its root, where real healing happens.

Support for Kidney Health

Cat body showing kidney location

If you’re caring for a pet with kidney disease (CKD), research highlights something incredibly important: not all kidney-support diets deliver the same results, and omega-3 fatty acids may be one of the key differences. In one study, cats eating standard food lived a median of about 7 months after CKD diagnosis. Cats eating therapeutic kidney diets lived significantly longer, about 9 months more on average. But the most striking finding was that the longest survival (around 23 months) occurred in cats fed a diet with optimal EPA levels, a biologically active omega-3 fatty acid. This suggests that beyond basic dietary changes, targeted nutritional support can dramatically influence how long and how well cats live with kidney disease.

This reinforces why high-quality omega-3 supplementation matters. EPA (and its partner DHA) aren’t just general wellness nutrients; they actively help reduce kidney inflammation, support blood flow to the kidneys, and slow the progression of damage over time. However, not all omega-3 products are created equal. Many contain low levels of EPA, are poorly absorbed, or are prone to oxidation, all of which limit their effectiveness.

For pets with kidney concerns, you want a clean, well-sourced marine omega-3 supplement with meaningful levels of EPA, ideally in a form that’s easy to absorb and appropriate for feline metabolism. Adding a properly formulated omega-3 supplement to your cat or small dog’s routine can be one of the most impactful steps you take to support kidney health and longevity. When combined with a moisture-rich, species-appropriate diet and regular veterinary monitoring, omega-3s become part of a comprehensive, proactive strategy, not just to manage kidney disease, but to improve quality of life along the way.

The Importance of Choline

Choline is one of those critically important, often overlooked nutrients in both human and animal nutrition. It plays a foundational role in cellular health, and it’s naturally present in our herring caviar oil, where it exists as part of the phospholipid structure. This is especially important because phospholipid-bound nutrients are highly bioavailable, meaning they’re easily absorbed and efficiently used by the body, integrating directly into cell membranes where they’re needed most.

At the cellular level, choline is essential for maintaining the integrity and function of every cell in the body. It supports the production of phosphatidylcholine, one of the primary building blocks of cell membranes, and plays a key role in mitochondrial health, which directly impacts energy production and overall vitality. Choline is also critical for neurologic function. It’s required to produce acetylcholine, a neurotransmitter involved in memory, learning, muscle control, and cardiovascular regulation.

For cats and small dogs, this translates to support for cognitive function, healthy aging, mobility, and nervous system balance, all of which become increasingly important as pets grow older or face chronic health challenges.

cat eating raw food bowl

Choline also provides metabolic and liver support, particularly beneficial for cats and small dogs prone to metabolic stress. It helps regulate fat metabolism by ensuring cholesterol is properly transported out of the liver, reducing the risk of fatty liver changes—a concern especially in cats. In addition, it supports methylation pathways by helping convert homocysteine into methionine, promoting cardiovascular health, and reducing systemic stress. When choline is delivered in its natural phospholipid form from herring caviar, it provides a gentle, highly effective way to support brain, liver, and cellular health, making it a valuable addition to a proactive wellness plan for small companion animals.

Each dropper delivers a precise, easy-to-administer dose that can be added directly to your pet’s food. The naturally palatable marine profile makes it well accepted by even selective eaters, eliminating the struggle often associated with supplementing.

Every ingredient in Roe Mega is carefully chosen. The fish oils are sourced from small, cold-water species known for their purity and sustainability, and the formula is carefully crafted to maintain freshness and potency without unnecessary additives.

If you’re looking for a simple, effective way to support your pet’s long-term health, Roe Mega offers a targeted solution rooted in science and designed with your pet’s unique biology in mind.

Frequently ask questions

Why Do Cats Need Omega-3 Fatty Acids?

As obligate carnivores, cats rely on biologicallyappropriate fatstomaintainhealth at a cellular level. Omega-3 fatty acids, especially EPA and DHA, play a critical role in controlling inflammation, supporting skin and coat quality,maintainingjoint mobility, and promoting kidney, immune, and cognitive function.Mostmodern diets fall short in providingoptimallevels, so targeted supplementation can help bridge that gap and support long-term wellness.

Can Roe Mega Be Given to Dogs?

The omega-3 profile in Roe Mega is remarkable for both dogs and cats; the fatty acid ratios,
antioxidant support, and superior phospholipid bioavailability are beneficial for both species. The only reason the product is labeled for cats (rather than cats and dogs) is cost efficiency; the ingredients are exceptionally pure but also significantly more expensive than standard fish oil blends. Medium and large dogs would require much higher daily volumes, making the product impractical for most pet parents, from a cost standpoint, but perfectly suitable for dogs and cats under 20 pounds. The product contains 100mg of combined DHA/EPA; a general dose suggestion for health maintenance is 1 dropper for every 10 pounds of body weight daily, twice daily. 

What Makes Roe Mega Different From Other Fish Oil Supplements?

Most fish oil supplements provide omega-3s in an ethyl ester form, but Roe Mega delivers them in the most bioavailable form: a phospholipid-bound form from caviar oil, which is easier for your cat’s body to digest, absorb, and utilize. I formulated this product to support your cat’s healthy physiology, combining caviar oil with clean, sustainably sourced fish oil from sardines, anchovies, and mackerel to create a more effective, bioavailable solution.Roe Mega is also third-party tested for heavy metals and contaminants. 

How Can This Supplement Benefit My Pet’s Health?

Roe Mega supports whole-body health, improves skin and coat quality, reduces shedding, and enhances comfort in pets with joint stiffness. It also provides important support for cell membrane stability, supporting kidney health, cardiovascular function, immune balance, and cognitive wellbeing, especially in aging cats. Because it works at the cellular level, it provides whole-body cellular support rather than targeting a single issue.

What Role Does Astaxanthin Play in This Formula?

Astaxanthin is a powerful antioxidant, 100 times more potent than vitamin E, that helps protect your pet’s cells from oxidative stress. It works synergistically with omega-3 fatty acids to support a balanced inflammatory response and promote brain, skin, and kidney health. It also plays an important role in stabilizing and naturally preserving the delicate oils in the formula, preventing oxidation and helping maintain freshness and potency without synthetic additives.

What Are SPMs?

Specialized pro-resolving mediators (SPMs) are bioactive compounds made from EPA and DHA that actively turn off inflammation and promote tissue healing. Not all fish oils contain them because SPMs are fragile and require specific processing to preserve or preform them, and most standard oils only provide precursors,not the finished mediators. Roe Mega was formulated to specifically include these compounds, delivering the active molecules that help resolve inflammation at its source.

Why Does My Pet Need Choline?

Choline supports neurologic and liver function, and overall vitality. It supports the production of phosphatidylcholine, a primary building block of cell membranes, and plays a key role in mitochondrial health. It’s naturally present in our herring caviar oil, where it exists as part of the phospholipid structure. This is especially important because phospholipid-bound nutrients are highly bioavailable, meaning they’re easily absorbed and efficiently used by the body, integrating directly into cell membranes where they’re needed most.

Is Roe Mega Easy to Use?

Yes, it is designed to be both safe and simple to use. The liquid formula is precisely dosed so that it can be easily added to your pet’s cat’s food. Most pets cats accept it readily because of its natural marine flavor. It is appropriate for pets cats at all stages of life and doesn’t contain iodine, so it’s safe for cats with hyperthyroidism. Vets recommend discontinuing all supplements prior to surgery.

Why Is Glass Packaging Important?

Oils stored in plastic containers can become contaminated with microplastics and oxidize overtime.That’s why Roe Mega is packaged in glass and contains protective astaxanthin, which helps maintain purity and protect the formula's integrity throughout use. Combined with sustainably sourced ingredients and careful formulation, this ensures your cat receives a clean, high-quality supplement you can feel confident about.

Is it Safe to Give my Pet More Than One Product at a Time?

Yes. Each Proactive Paws formula is created with compatibility in mind, making it safe and effective to use them together. We recommend starting each supplement one at a time, allowing the body to adjust to the new supplement beforeadding the next. For sensitive animals, you can start at half or a quarter of the dose and work up to the suggested amount.If your cat is finicky, start with a drop a day of Roe Mega, and increase daily.